Research and Development of New Products
Competence in biotechnology, from patent to product
More potency against bladder cancer, more protection against tuberculosis
Pioneering in
recombinant BCG technology
Scenario of Bladder Cancer Treatment with BCG
There is a worldwide shortage of BCG-derived products with a large unmet demand
Demand
450 thousand
cases per year
worldwide
10 thousand
cases per year
reported in Brazil
70%
of cases:
BCG recommended
Opportunity
30%
relapse of treatment
with Onco BCG
3 million
doses is the estimated
world demand
U$ 450 million
is the estimated value
of the world market
Recombinant technology applied to BCG strengthens and transforms its power to activate the immune system.
In the 1970s, it made history again by becoming the gold standard in the treatment of bladder cancer.
Bacillus Calmette-Guérin (BCG) entered medical history in 1921 as a vaccine against tuberculosis.
Bacillus Calmette-Guérin (BCG)
A new recombinant
BCG for bladder cancer treatment
Improved treatment
The Onco rBCG has genetic modifications that increases the immune response and reduces the tumors.
Normal bladder
Bladder with tumor
Bladder with tumor treated with Onco BCG
Bladder with tumor treated with recombinant BCG
Exceptional results
Experimental results demonstrate significant improvement in antitumor properties
46% of subjects cured with Recombinant Onco BCG
against 0% among those treated with Onco BCG
Recombinant Onco BCG development path
COMPLETE
Discovery
Expected results
BCGene will carry out the product development stages to provide the patent licensing for a company interested in producing and commercializing the new Onco rBCG.
USD 45 million
Estimated revenue for the producing company by the 5th year of production
COMPLETE
Pre-clinical
Launch of BCGene
ONGOING
Process Development Scale-up
GMP production Submission to ANVISA
Obtain approval for clinical trials
Clinical trials
Licensing
Industrial production
Production and marketing
Contact
Av. Brigadeiro Faria Lima, 3144, conj. 31
Jardim Paulistano – São Paulo, SP, Brasil
01451-000
