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Scenario of Bladder Cancer Treatment with BCG

There is a worldwide shortage of BCG-derived products with a large unmet demand

Demand

450 thousand

cases per year
worldwide

10 thousand

cases per year
reported in Brazil

70%

of cases:
BCG recommended

Opportunity

30%

relapse of treatment
with Onco BCG

3 million

doses is the estimated
world demand

U$ 450 million

is the estimated value
of the world market

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BCG recombinante
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A new recombinant
BCG for bladder cancer treatment

Improved treatment

The Onco rBCG has genetic modifications that increases the immune response and reduces the tumors.

Normal bladder
Bladder with tumor
Bladder with tumor treated with Onco BCG
Bladder with tumor treated with recombinant BCG

Exceptional results

Experimental results demonstrate significant improvement in antitumor properties

46% of subjects cured with Recombinant Onco BCG

against 0% among those treated with Onco BCG

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