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Scenario of tuberculosis in the world

A dangerous
disease

 

Tuberculosis is among the Top-10 causes of death in the world. Brazil is among the countries with a high incidence of tuberculosis.

A demand
problem

Conventional BCG, traditionally used as a vaccine against tuberculosis, has an irregular global supply.

It was the most important cause of death from a single infectious agent (before the Sars-CoV-2 pandemic)

An efficiency
problem

Conventional BCG offers good protection against childhood tuberculosis but has reduced protection against pulmonary tuberculosis in adults.

Demanda

Opportunities

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1.7 million

deaths per year worldwide

4,500

deaths in Brazil,
200 new cases a day

Affects

mainly developing countries

BCG shows

reduced protection
in adults

150 million

doses is the estimated
world demand

10 million

doses is the estimated
demand for Brazil

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Vaccine with greater protection

The new recombinant BCG vaccine for tuberculosis (rBCG-AdjTB – rBCG expressing an adjuvant) has shown greater protection against tuberculosis infection in experimental animals.

Recombinant BCG as improved vaccine against tuberculosis

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tuberculose 2
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